Objective of the study
To investigate the relation between nutrition, fiber-intake, microbiome and neurogenic bowel problems in SCI patients
What is the percentage of patients wit SCI not satisfied with their bowel management?
What is currently known on the microbiome of patients with SCI or MS?
Can probiotics influence neurogenic bowel problems in patients with SCI?
What is the dietary and fiber-intake of patients with SCI? Is there a relation with neurogenic bowel problems?
How this is investigated
We will look at the satisfaction of SCI patients with their bowel function. To do this we will use the bowel topic of the Dutch Spinal Cord Injury Data Set (NDD).
We will do an assessment of nutrition and fiber-intake of SCI patients and look at the relation with bowel problems. We will ask 30 patients with a (chronic) SCI about their nutrition and fiber-intake, using “the Eetscore”. Furthermore, we will ask about neurogenic bowel problems.
A systematic review will be done on what is currently known on the microbiome of spinal cord injury patients and patients with MS.
We want to examine if the microbiome in SCI patients influences neurogenic bowel problems. We have started a double-blind randomised placebo-controlled trial on the effect of a multispecies probiotic on the incidence of antibiotic-associated diarrhoea in persons with spinal cord injury.
The study is performed by Willemijn Faber (rehabilitation physician of Heliomare). She is supported by Prof. dr. B.J.M. Witteman (Wageningen University), dr. R. Winkels (Wageningen University), dr. J. Stolwijk-Swuste (De Hoogstraat) en dr. J. Nachtegaal (Heliomare).
The project is financed by Heliomare
Faber W, Stolwijk-Swuste J, Van Ginkel F, Nachtegaal J, Zoetendal E, Winkels R, Witteman B. Faecal microbiota in patients with neurogenic bowel dysfunction and spinal cord injury or multiple sclerosis-a systematic review. Journal of Clinical Medicine 2021, 10(8), 1598.
Start: january 2017
Planned end: 2023
Mw. W. Faber